DUMBLE, MELISSA,GILMER, TONA,KUMAR, RAKESH,LEBOWITZ, PETER F.,MORRIS, SHANNON RENAE,LAQUERRE, SYLVIE
申请号:
MX2012004139
公开号:
MX2012004139A
申请日:
2010.10.08
申请国别(地区):
MX
年份:
2012
代理人:
摘要:
The present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a cancer treatment method that includes administering N-{3-[5-(2-Amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1, 3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide or a pharmaceutically acceptable salt thereof, and N-{(1S)-2-amino-1-[(3,4-difluorophenyl)methyl]ethyl}-5-c hloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-furancarbox amide, or a pharmaceutically acceptable salt thereof, to a human in need thereof.La presente invención se refiere a un método para tratar cáncer en un ser humano y a combinaciones farmacéuticas útiles en tal tratamiento; en particular, el método se refiere a un tratamiento de cáncer que incluye administrar N-{3-[5-(2-amino-4-pirimidinil)- 2-(1,1-dimetiletil)-1,3-tiazol-4-iI]-2-fluorofenil}-2,6-difluorob encensulfonamida o una sal farmacéuticamente aceptable de la misma, y N-{(1S)-2-amino-1-[(3,4-difluorofenil)metil]etil}-5-cloro -1-metil-1H-pirazol-5-il)-2-furancarboxamida o una sal farmacéuticamente aceptable de la misma, a un ser humano que lo necesite.