SOUERS ANDREW,HANSEN TODD M.,WANG LE,DOHERTY GEORGE,WANG XILU,TAO ZHI-FU,BRUNKO MILAN,KUNZER AARON R.,WENDT MICHAEL D.,SONG XIAOHONG,FREY ROBIN,SULLIVAN GERARD M.,JUDD ANDREW
申请号：
NZ62306812
公开号：
NZ623068A
申请日:
2012.10.11
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed are compounds having Formula (I) which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein. In one embodiment, the compound of Formula (I) is 6-[8-(1,3-benzothiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl]-3-(1-benzyl-1H-pyrazol-4-yl)pyridine-2-carboxylic acid.
