Methods and uses of low dosage nonmetabolizable D-glucose analogs and mannose analogs such as 2-deoxy-D-glucose, 5-thio-D-glucose, 2-fluoro-2-deoxy-D-glucose, 2-chloro-2-deoxy-D-glucose, 2-bromo-2-deoxy-D-glucose, 2-deoxy-2-fluoro- mannose, 2-deoxy-2-chloro-mannose, 3-deoxy mannose, 4-deoxy mannose, and 2,3 didioxy mannose, for the treatment of tumors.Linvention concerne des procédés et utilisations danalogues de D-glucose et danalogues de mannose non métabolisables de faible dosage tels que 2-désoxy-D-glucose, 5-thio-D-glucose, 2-fluoro-2-désoxy-D-glucose, 2-chloro-2-désoxy-D-glucose, 2-bromo-2-désoxy-D-glucose, 2-désoxy-2-fluoro-mannose, 2-désoxy-2-chloro-mannose, 3-désoxy mannose, 4-désoxy mannose et 2,3-didioxy mannose, pour le traitement de tumeurs.