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RON BINDING CONSTRUCTS AND METHODS OF USE THEREOF
专利权人:
发明人:
BLANKENSHIP JOHN W,TAN PHILIP,NATARAJAN SATEESH KUMAR,ALGATE PAUL A,CHENAULT RUTH A
申请号:
IN6220/CHENP/2012
公开号:
IN2012CN06220A
申请日:
2012.07.16
申请国别(地区):
IN
年份:
2014
代理人:
摘要:
This disclosure provides immunoglobulin binding molecules that specifically bind to human macrophage stimulating receptor (MST1 R also referred to herein as recepteur d origine Nantaise or RON) including antibodies and monospecific and multispecific single chain binding proteins having one or more other domains such as one or more antibody constant region domains. Also provided are therapeutic applications of such binding proteins such as for the treatment of cancer and inflammatory disorders.
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