A temperature sensing patch that is easy to use and capable of efficiently monitoring temperature change in human, body for a long time, capable of being used with a reading device, comprising the temperature sensing patch configured to attach to human skin, comprising a housing, a circuit board, a temperature sensing unit electrically connected with the circuit board, a battery, a processor chip, at least a memory unit, and at least a port; wherein the processor chip can automatically turn on the temperature sensing patch and reset the previous data by a predetermined program, rather than through a manual switch, when the temperature sensing patch is removed from the reading device.