use of staurosporine derivatives as inhibitors of tyrosine kinase flt3 receptor activity in the treatment of acute myeloid leukemia and high-risk myelodysplastic syndromes
"staurosporine derivatives as inhibitors of tyrosine kinase flt3 receptor activity". the present invention relates to the use of staurosporine derivatives for the preparation of a drug for the treatment of diseases involving the unregulated activity of flt3 tyrosine kinase receptors, especially for the curative and / or prophylactic treatment of leukemias and myelodysplastic syndromes, and to a method of treating diseases involving the unregulated activity of flt3 tyrosine kinase receptors."derivados de estaurosporina como inibidores da atividade de receptores flt3 de tirosina cinase". a presente invenção refere-se ao uso de derivados de estaurosporina para a preparação de uma droga para o tratamento de doenças envolvendo a atividade desregulada de receptores flt3 de tirosina cinase, especialmente para ao tratamento curativo e/ou profilático de leucemias e síndromes mielodisplásicas, e a um método de tratamento de doenças envolvendo a atividade desregulada de receptores flt3 de tirosina cinase.
