ROBERT SHALWITZ;AKEBIA THERAPEUTICS INC.;JOSEPH H. GARDNER;JOHN M. JANUSZ
发明人:
ROBERT SHALWITZ,JOSEPH H. GARDNER,JOHN M. JANUSZ
申请号：
IL22982713
公开号：
IL229827A
申请日:
2013.12.05
申请国别(地区):
IL
年份:
2017
代理人:
摘要：
The invention relates to a composition for use in a method for treating cancer in a subject. The composition comprises the compound {[5-(3-fluorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid or a pharmaceutically acceptable salt thereof. The invention further provides in vitro or ex vivo methods for increasing levels of sVEGF-1 secreted from a cell and for decreasing levels of PGK in a cell comprising administering to the cell an effective amount of {[5-(3-fluorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid. {[5-(3-fluorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid has the formula
