Disclosed is the use of 7á- or 7â-hydroxyepiandrosterone or an ester thereof, for the manufacture of a medicament for the treatment or prophylaxis of an inflammatory condition selected from the group of: peripheral arterial diseases and their sequelae such as critical limb ischaemia coronary artery disease and its sequelae atherosclerotic renal artery stenosis diabetes mellitus and its sequelae including type 2 diabetes and its sequelae inflammatory skin conditions multiple sclerosis inflammatory bowel disease rheumatoid arthritis and primary and secondary osteoarthritis and their sequelae inflammatory diseases characterised by degeneration of articular cartilage acromegaly and inflammation or inflammatory diseases of peripheral organs selected from the liver or kidney and inflammatory airway diseases.