University of Louisville Research Foundation, Inc.;Georgia Tech Research Corporation
发明人:
Haval SHIRWAN,Andres J. GARCIA,Esma S. YOLCU,Hong ZHAO,Devon HEADEN
申请号：
US16492441
公开号：
US20200046780A1
申请日:
2018.03.09
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Described herein are FasL-engineered biomaterials, as well as methods of making and using such FasL-engineered biomaterials, such as for immunomodulation, such as for inducing immunosuppression and specific immune tolerance, such as for preventing or reducing the risks of rejection of cellular or tissue grafts and/or the treatment of autoimmune disorders such as Type I diabetes. In specific embodiments, the FasL-engineered biomaterials are biotinylated microgels bound to SA-FasL.
