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USE AS IMMUNE ENHANCER OR PHARMACEUTICAL COMPOSITION FOR TREATMENT OF DEMENTIA, COMPRISING PHYTOSPHINGOSINE-1-PHOSPHATE OR DERIVATIVE THEREOF
专利权人:
LTD.;AXCESO BIOPHARMA CO.
发明人:
Myeong Jun CHOI
申请号:
US16340465
公开号:
US20200046829A1
申请日:
2017.04.07
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed in the present invention are a use as an immune enhancer of phytosphingosine-1-phosphate (P1P), O-cyclic P1P (cP1P), N-acetylphytosphingosine-1-phosphate (NAPS-1-P), and pharmaceutically acceptable salts thereof, and a pharmaceutical composition or vaccine for treating dementia, comprising such substance on the basis of a neuronal cell death inhibitory effect. The substance according to the present invention exhibits an effect of enhancing Th2 immune response and inhibiting Th1 immune response and has an effect of protecting neurons as well, and thus can be useful as an immune enhancer to help the production of antibodies for the development of a dementia vaccine, as well as an agent for preventing or treating dementia.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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