NIKOLOVSKA-COLESKA, ZANETA,BAJWA, NAVAL,LIAO, CHENZHONG,MIAO, LEI
申请号:
EP13767518
公开号:
EP2831067A4
申请日:
2013.03.29
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a [(1-Piperazinyl)-4-pyridinylmethyl]-Naphtho[1,2-b]furan structure which function as inhibitors of Mcl-1 protein, and their use as therapeutics for the treatment of cancer and other diseases.