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ТЕРАПЕВТИЧЕСКОЕ ПРИМЕНЕНИЕ 1-[2-(2,4-ДИМЕТИЛФЕНИЛСУЛЬФАНИЛ)ФЕНИЛ]ПИПЕРАЗИНА
专利权人:
Х. ЛУНДБЕКК А/С (DK)
发明人:
ДРАГХЕИМ Марианне (DK),ФЛОРЯ Йоана (DK)
申请号:
RU2013112890/15
公开号:
RU2013112890A
申请日:
2011.08.22
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. Use of 1- [2- (2,4-dimethylphenylsulfanyl) phenyl] piperazine and pharmaceutically acceptable salts thereof in the long treatment of CNS disorders in a patient, wherein said treatment is associated with a slight increase in body weight or a full otsutstviem.2. Use of 1- [2- (2,4-dimethylphenylsulfanyl) phenyl] piperazine and pharmaceutically acceptable salts thereof in the treatment of CNS disorders in a patient who previously received (or is still receiving) medical treatment of the disease, and that drug therapy was discontinued ( or should be stopped) due to undesirable side effects associated with the mass tela.3. Use of 1- [2- (2,4-dimethylphenylsulfanyl) phenyl] piperazine and pharmaceutically acceptable salts thereof in the treatment of CNS disorders in a patient who has overweight (BMI) .4. Use according to claim 3, wherein said patient has a BMI of 25.5. Use of 1- [2- (2,4-dimethylphenylsulfanyl) phenyl] piperazine and pharmaceutically acceptable salts thereof in the treatment of CNS disorders in a patient who is also suffering additional disease in which the need to avoid weight increase tela.6. Use according to claim 5, wherein said patient also suffers from Type II diabetes mellitus, hypertension or coronary heart disease, or refrains from nikotina.7. Use according to any one of 1-6, wherein said CNS disorder is selected from depression, anxiety, chronic pain and zavisimosti.8. Use according to any one of 1-6, wherein said pharmaceutically acceptable salt is the hydrobromic solyu.9. A method of long-term treatment of CNS disorders comprising administering a therapeutically effective amount of a 11. Применение 1-[2-(2,4-диметилфенилсульфанил)фенил] пиперазина и его фармацевтически приемлемых солей в долгосрочном лечении заболевания ЦНС у пациента, где указанное лечение связано с незначительным увеличением массы тела или его полным отсутствием.2. Применение 1-[2-(2,4-диметилфенилсульфанил)фенил] пиперазина и его фармацевтически приемлемых солей в лечени
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