PRICE, STEPHEN,HEALD, ROBERT,LEE, WENDY,ZAK, MARK E.,HEWITT, JOANNE FRANCES MARY
申请号：
PL08869100
公开号：
PL2222675T3
申请日:
2008.12.18
申请国别(地区):
PL
年份:
2014
代理人:
摘要：
The invention relates to imidazopyridines of formula 1 with anti-cancer and/or anti-inflammatory activity and more specifically to imidazopyridines which inhibit MEK kinase activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth or treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.
