The present invention relates to the field of plant breeding, particularly to the development of hybrid pepper variety 10BR46100. Pepper plants of the invention may exhibit a combination of traits including red colored blocky fruits, Tobamovirus resistance against Tobamovirus Pathotype 0 (P0) and Tobamovirus Pathotype 1-2 (P1-2), and resistance against Phytophthora capsici, representative seed of which have been deposited under NCIMB Accession No. 41824.