This paper provides an ophthalmic composition.In some embodiments, the ophthalmic composition comprises a low concentration of an ophthalmic agent for the treatment of an ophthalmic disease or condition; and an ophthalmically acceptable carrier, wherein the ophthalmic agent is substantially uniformly distributed throughout the ophthalmic acceptable carrier.Further disclosed herein includes an ophthalmic composition comprising a low concentration ophthalmic agent and deuterated water.Methods for preventing or preventing the development of myopia by applying an effective amount of ophthalmic composition as described herein to the eyes of an individual in need are also disclosed.本文提供了一種眼用組合物。在一些實施方案中,該眼用組合物包含低濃度的用於治療眼科病症或病況的眼用劑;以及眼科上可接受的載體,其中該眼用劑在遍及眼科上可接受的載體中基本均勻分布。本文進一步公開的內容包括包含低濃度的眼用劑和氘化水的眼用組合物。本文還公開了通過向有需要的個體的眼睛施用有效量的如本文描述的眼用組合物來阻止或預防近視發展的方法。