CHO, Jae-Pyoung,LEE, Pung-Sok,LEE, Seul-A,JEONG, Min-Ho,LEE, Mase
申请号:
PH12014502609
公开号:
PH12014502609B1
申请日:
2014.11.21
申请国别(地区):
PH
年份:
2015
代理人:
摘要:
The present disclosure provides a pharmaceutical composition in multilayer-coated form including an omega-3 fatty acid or an alkyl ester thereof and a statin-based drug, and more particularly, a pharmaceutical composition for oral administration including: (a) a gelatin capsule core containing an omega-3 fatty acid or an alkyl ester thereof; (b) a first coating layer formed by coating, on the gelatin capsule core, hydroxypropyl methylcellulose and a copolymer of butyl methacrylate, (2-dimethylaminoethyl) methacrylate, and methyl methacrylate at a weight ratio of 1:2:1; and (c) a second coating layer formed by coating, on the first coating layer, a coating solution containing a statin-based drug.