The present invention belongs to the pharmaceutical field, and provides crystalline forms, solvates and the crystalline forms thereof of the compound (S)-4-amino-6-((1-(3-chloro-6-phenylimidazo[1,2-b]pyridazin-7-yl)ethyl)amino)pyrimidine-5-carbonitrile, and the pharmaceutical compositions comprising the same as well as the methods of preparing the same and the use thereof.本發明屬於藥學領域,提供了化合物(S)-4-胺基-6-((1-(3-氯-6-苯基咪唑并[1,2-b]噠嗪-7-基)乙基)胺基)嘧啶-5-甲腈的晶型、溶劑合物及其晶型,其藥物組合物、及其製備方法和應用。