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Cyclic Di-Nucleotide Induction of Type I Interferon
专利权人:
The Regents of the University of California
发明人:
Russell E. Vance,Ming C. Hammond,Dara Burdette,Elie J. Diner,Stephen C. Wilson
申请号:
US16279950
公开号:
US20190292216A1
申请日:
2019.02.19
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Methods and compositions are provided for increasing the production of a type I interferon (IFN) in a cell. Aspects of the methods include increasing the level of a 2′;-5′; phosphodiester linkage comprising cyclic-di-nucleotide in a cell in a manner sufficient to increase production of the type I interferon (IFN) by the cell. Also provided are compositions and kits for practicing the embodiments of the methods.
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