用經不可切割接頭連接的細胞結合劑美登木素生物鹼偶聯物

• 收藏
• 分享

专利权人:

伊繆諾金公司;IMMUNOGEN, INC.

发明人:

Rita STEEVES,Robert LUTZ,Ravi CHARI,Hongsheng XIE,Yelena KOVTUN,R‧查裡,H‧謝,Y‧科夫通

申请号：

HK18104043.9

公开号：

HK1244452A

申请日:

2008.02.27

申请国别(地区):

HK

年份:

2018

代理人:

摘要：

The present invention discloses a method for targeting maytansinoids to a selected cell population, the method comprising contacting a cell population or tissue suspected of containing the selected cell population with a cell-binding agent maytansinoid conjugate, wherein one or more maytansinoids is covalently linked to the cell-binding agent via a noncleavable linker and the cell-binding agent binds to cells of the selected cell population.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/