The present invention relates to a method and a diagnostic kit for analysing the inflammatory state and endometrial receptivity in women suffering from unexplained spontaneous recurrent abortion and/or infertility, and to alpha-lipoic acid for use in the treatment or assistance in the treatment of endometrial inflammation. The invention is based on analysis of the ratio between the levels of expression of the NALP-3 and thrombomodulin proteins in the endometrium. A ratio of greater than 1 is indicative of an increased condition of endometrial inflammation compared to a fertile subject and is associated with reduced endometrial receptivity.
