Biomarkers and their use in the diagnosis and treatment of autism

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专利权人:

オーティズム バイオテック リミテッド

发明人:

モメニ ナギ,ペルッソン ベント エル．,ペルッソン ベント エル.

申请号：

JP2013544428

公开号：

JP5960717B2

申请日:

2011.12.13

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

A new biomarker, a peptide having sequence SSKITHRIHWESASLLR*, wherein the side chain of the C-terminal arginine denoted with the asterisk is lacking the NH2- C&boxH；NH moiety normally present in the side chain. Usefulness of the biomarker in the diagnosis of neurological and/or neuropsychiatric disorders (in particular autism) is disclosed, as well as are methods for determining the concentration of the new biomarker and antibodies directed to the new biomarker. Treatment of autism, comprising administering a complement factor I inhibitor to the subject.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/