An endoscope (1) having a handle with a handle housing (2) and an insertion tube (3) extending from said handle (2) and terminating in a tip part (4) at the distal end of the endoscope (1). A working channel and having a distal end and a proximal end extends within the insertion tube (3). The endoscope further comprises motion transfer means (53, 54) extending within said working channel and adapted to operate a tool (55) at the exit port of the tip part (4) in response to the activation of an operating member (22). The working channel comprises a generally tubular working channel wall. The distal working channel end comprises an exit port at the tip part (4) at the distal end of the endoscope (1). The proximal working channel end comprises an end sealing means accommodated within the handle housing (2). An entry port is provided between the distal working channel end and the proximal working channel end.