Maria Sasgary,Maria Schuster,Hans-Peter Schwarz,Birgit Reipert,Gerhard Antoine,Hartmut Ehrlich
申请号：
US13071190
公开号：
US20120082987A1
申请日:
2011.03.24
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates, in general, to development of non-human transgenic animals expressing a human blood clotting factor, such as Factor VIII, Factor VII, Factor IX and von Willebrand factor. The invention further provides methods of detecting immunogenic events against human blood clotting factor using the transgenic animals described.
