Suri, Anish,Sheriff, Steven,Suchard, Suzanne,Yamniuk, Aaron,Krystek, Stanley,Tamura, James,Bryson, James,Grant, Steven,Drew, Philip
申请号：
AU2016202672
公开号：
AU2016202672A1
申请日:
2016.04.27
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
#$%^&*AU2016202672A120160526.pdf#####Antibody polypeptides and fragments thereof comprising a first variable domain, wherein said antibody polypeptides specifically bind to an epitope of human CD40 and compete with the binding of domain antibody (dAb) BMS3h-56-269 to CD40, without exhibiting CD40 agonist activity. Also provided are compositions comprising such antibodies and uses of these compositions in methods of treating diseases involved in CD40 activity, including autoimmune diseases, transplant rejection and allergic responses.
