The invention concerns a method and system for analyzing a liquid sample containing solid matter. The method comprises fractionating the sample according to particle sizes and/or masses of the solid matter so as to produce sample fractions, and measuring at least one physical or chemical property of at least one of said sample fractions. According to the invention the sample is conducted to a disintegration channel having one or more depressions, and a liquid flow having a non-constant temporal velocity profile is applied through the disintegration channel, in order to gradually take solid matter of the sample with the liquid flow from said one or more depressions for providing said sample fractions. The invention allows for efficient fractionation of samples, which cannot be fractionated using conventional field flow fractionation, for example.
