Boice, Michael Henry,Wendel, Hans Guido,Salloum, Darin
申请号:
AU2016243043
公开号:
AU2016243043A1
申请日:
2016.04.04
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
In some aspects the present invention provides methods for the treatment of B-cell lymphomas. Some such methods involve administration of HVEM ectodomain polypeptides, anti-HVEM antibodies, or anti-BTLA antibodies to subjects in need thereof. Some such methods involve use of CAR T cells, such as CD19-specific CAR T cells. The present invention also provides compositions useful in such methods. These and other embodiments of the present invention and described further herein.