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Cytotoxicity mediation of cells evidencing surface expression of CD44
专利权人:
F. Hoffmann-La Roche AG
发明人:
Young, David S.F.,Findlay, Helen P.,Hahn, Susan E.
申请号:
AU2011200789
公开号:
AU2011200789B2
申请日:
2011.02.24
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
#$%^&*AU2011200789B220140130.pdf#####C NRPortbl DC0FJB 3492349l .DOC-24/02/2011 ABSTRACT CYTOTOXICITY MEDIATION OF CELLS EVIDENCING SURFACE EXPRESSION OF CD44 5 The use of anti-CD44 monoclonal antibody H460-16-2 for the diagnosis and treatment of cancerous tumors, and binding assays which determine the presence of cells which express a CD44 antigenic moiety which specifically binds the monoclonal antibody H460-16-12. The monoclonal antibody is optionally used in combination with one or more 10 chemotherapeutic agents, as a means for initiating the cytotoxic response to tumors.
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