The utility model relates to a diaper structure with a waterproof moisture sensing device. A wireless air humidity sensing module is placed in a waterproof and dustproof box, and then a waterproof and dustproof box containing the wireless air humidity sensing module is arranged on the outside of the urine collecting area of the diaper body. The wireless air humidity sensing module senses the urine humidity state of the urine collecting area, and passes the sensing results through the wireless air humidity sensing module. The transmission protocol is transmitted to a monitoring device for the purpose of warning notice, waterproof and dustproof.一種具有防水感測濕氣裝置之尿布結構,將一無線空氣濕度感測模組置入一防水防塵盒中,再將容置有該無線空氣濕度感測模組之防水防塵盒裝設在一尿布本體之集尿區的外側處,由該無線空氣濕度感測模組對該集尿區進行尿濕狀態感測,並將感測結果透過該無線傳輸協定傳送至一監控裝置,以達到警示通知及防水防塵之目的。