A method for determining a calibrated aortic pressure waveform from a brachial cuff waveform involves the use of one or more generalized transfer functions. The one or more generalized transfer functions are specific for predetermined brachial cuff pressure ranges, such as below diastolic pressure, between diastolic and systolic pressure, and above systolic pressure. The brachial cuff is inflated to a pressure within the pressure range appropriate for the generalized transfer function to be applied to the brachial cuff waveform to generate the aortic pressure waveform. In some circumstances, it may be necessary to use a calibration transfer function to generate a calibrated aortic waveform. In other circumstances, the calibration transfer function is not necessary.
