Stable liquid formulations containing picosulfate and magnesium citrate are provided. The formulations are useful to treat constipation or for the clearance of the bowel prior to X-ray examination, endoscopy or surgery.本發明提供包含匹可硫酸鹽(picosulfate)及檸檬酸鎂之安定液體調配物。該等調配物可用於治療便秘或可用於X射線檢查、內視鏡檢查或手術前的清腸。