Mayo Foundation for Medical Education and Research;University of Pittsburgh - Of the Commonwealth System of Higher Education
发明人:
Yasuhiro Ikeda,Claire A. Schreiber,Toshie Sakuma,Sara J. Holditch,Kazunori Koide
申请号:
US15318618
公开号:
US20170112946A1
申请日:
2015.06.12
申请国别(地区):
US
年份:
2017
代理人:
摘要:
This document relates to methods and materials for increasing viral vector infectivity. For example, methods and materials for using spliceosome inhibitors (e.g., U2 snRNP spliceosome inhibitors such as meayamycin B or pladienolide derivative E7107) to increase viral vector (e.g., adeno-associated virus-based vector) infectivity are provided.