Use of adapalene or one of its salt for the preparation of a pharmaceutical composition to be administered in combination or in association with benzoyl peroxide for reducing the number of acne injuries. Independent claims are included for: (1) a kit comprising two components such as a first component comprising the adapalene or its salt and a second component comprising the benzoyl peroxide and (2) a product comprising a container defining a compartment and the composition laid inside the compartment, where the container being closed by a closure unit. ACTIVITY : Antiseborrheic Dermatological. MECHANISM OF ACTION : None given.