Provided is an acetaminophen and tramadol compound oral solution having an acetaminophen having a weight percentage of 1.447 wt % to 6.702 wt %, a tramadol having a weight percentage of 0.167 wt % to 0.773 wt %, and a solvent system, weighted 90.828 wt % to 98.02 wt %, having a glycerin, a water and a polyethylene glycol, wherein the polyethylene glycol has a weight percentage of 17 wt % to 65 wt % of the total weight of the acetaminophen and tramadol compound oral solution that help ease difficulties for the aged, severe or dysphagia patients.
