FORME CRISTALLINE D'UN INHIBITEUR DU CANAL POTASSIQUE MÉDULLAIRE EXTERNE RÉNAL ET PROCÉDÉ DE PRÉPARATION ASSOCIÉ

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专利权人:

Jiangsu Hengrui Medicine Co.; Ltd.

发明人:

申请号：

EP18886529.9

公开号：

EP3722293A1

申请日:

2018.12.05

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present invention provides a crystal form of a renal outer medullary potassium channel inhibitor and a preparation method thereof. In particular, the present invention provides crystal form III of a L-tartrate of a renal outer medullary potassium channel (ROMK) inhibitor (I) and a preparation method thereof. The crystal form III has good chemical stability and crystal form stability, and the crystallization solvent used has low toxicity and residue. Thus, the present invention can be better used in clinical treatment.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/