BAETTIG, URS,D'SOUZA, ANNE-MARIE,HUNT, PETER,PRESS, NEIL JOHN,WATSON, SIMON JAMES
申请号：
ES09804555
公开号：
ES2458596T3
申请日:
2009.08.03
申请国别(地区):
ES
年份:
2014
代理人:
摘要：
A compound of formula I ** Formula ** or pharmaceutically acceptable solvates, hydrates or salts thereof, wherein R1 is H, a 3 to 10 membered carbocyclic group, optionally substituted by one or more Z groups, a 3-heterocyclic group 10-member, optionally substituted by one or more Z groups, carbocyclic group (C1-C4 alkyl) of 3 to 10 members, optionally substituted by one or more Z groups, heterocyclic group (C1-C4 alkyl) of 3 to 10 members, optionally substituted by one or more Z groups, C1-C6 alkyl optionally substituted by one or more halogen atoms, OH or CN groups, C1-C6 alkoxy optionally substituted by one or more halogen atoms or OH groups, or an ether group that it contains from 2 to 10 carbon atoms and 1 to 3 oxygen atoms, wherein the ether group is optionally substituted by one or more substituents each independently selected from OH, halogen, a 3 to 10 membered carbocyclic group, optionally substituted by one or more Z groups and a 3-10 membered heterocyclic group, optionally substituted by one or more Z groups； R2 is a 3 to 10 membered carbocyclic group, optionally substituted by one or more Z groups, a 3 to 10 membered heterocyclic group, optionally substituted by one or more Z groups, a 3 to 10 carbocyclic group (C1-C4 alkyl) members, optionally substituted by one or more Z groups, heterocyclic group (C1-C4 alkyl) of 3 to 10 members, optionally substituted by one or more Z groups, C1-C6 alkyl optionally substituted by one or more halogen atoms, OH groups or CN, C1-C6 alkoxy optionally substituted by one or more halogen atoms or OH groups, or an ether group containing from 2 to 10 carbon atoms and 1 to 3 oxygen atoms, wherein the ether group is optionally substituted by one or more substituents, each independently selected from OH, halogen, a 3 to 10 membered carbocyclic group, optionally substituted by one or more Z groups and a 3 to 10 membered heterocyclic group, optionally substituted by one or more groups Z； or R1 and R2 together with the carbon atom
