William H. Frey, II,Samuel Scott Panter,Leah Ranae Bresin Hanson,Annina Roeytenberg
申请号:
US12829844
公开号:
US09351927B2
申请日:
2010.07.02
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Pharmaceutical compositions for treating and/or pre-treating or preconditioning the animal central nervous system against the effects of Alzheimers Disease including the associated neurodegeneration and cognitive, behavioral and physical impairments. In one embodiment, an effective dose of deferoxamine (DFO) is administered to the upper one-third of the subject patients nasal cavity to effectively bypass the blood-brain barrier, thereby allowing application of the DFO dose directly to the central nervous system.