A described system includes a feature matching circuit that determines a correspondence between a present-location landmark subsurface feature of a body part of an individual patient and a candidate reference landmark subsurface feature of the individual patient body part. The present-location landmark subsurface feature has a first spatial relationship to a distal end portion of a body-insertable device deployed in the individual patient. The candidate reference landmark subsurface feature has a second spatial relationship to a particular selected target region of interest of at least two selected target regions of interest. An event data circuit generates data indicative of a proximity event that includes the distal end portion of a body-insertable device being proximate to the particular target region of interest. A list management circuit adds the proximity event to a proximity event list. A computer-readable media maintains informational data corresponding to the proximity event list.