Mie University;Biocomo Co., Ltd.;National Institute of Biomedical Innovation
发明人:
申请号:
EP10826901.0
公开号:
EP2497493A1
申请日:
2010.11.01
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
Disclosed is a intranasal spray-type tuberculosis vaccine, which has a high prophylactic effect on human tuberculosis, particularly adult tuberculosis. The nebulizable tuberculosis vaccine for intranasal administration comprises a paramyxovirus gene (particularly rhPIV2) having, integrated therein, a gene encoding an α antigen derived from an acid-fast bacterium (e.g., an α antigen derived from Mycobacterium kansasii or Mycobacterium bovis BCG), an analogue of the gene, or a variant of the gene which has an equivalent function to that of the gene.