Embodiments of the present disclosure relate generally to devices and systems for administering pharmaceutical, monitored and/or biological agents via nebulization to a subject. In certain embodiments, the present disclosure provides devices, methods and systems for biometric and diagnostic data acquisition and patient monitoring before, during, and after the nebulization and administration of pharmaceutical, monitored and/or biological agents to a subject. In yet other embodiments, devices, systems and methods disclosed herein provide for delivery of agents where patients have an increased level of control over the delivery of their medication and by providing healthcare providers with meaningful and accurate biometric and diagnostic data during treatment.