A multiple physiological signals sensing chip is provided. The multiple physiological signals sensing chip includes a substrate, a first light-emitting diode, a second light-emitting diode, a sensing array, and a processing unit. The substrate includes a contact surface touched by a finger. The first and second light-emitting diodes respectively emit red light and infrared light to the finger. The sensing array senses the red light or the infrared light reflected or refracted from the finger to obtain first physiological sensing signals according to a first sensing period or senses the red light and the infrared light reflected or refracted from the finger to obtain second physiological sensing signals according to a second sensing period. The first sensing period is shorter than the second sensing period. The processing unit respectively processes the first and second physiological sensing signals to obtain spatial information and energy information corresponding to the finger.