CHIANG KYLE P.,GARDINER ELISABETH,LAU CHING FUN,LO WING-SZE,GREVE JEFFREY,ASHLOCK MELISSA,MENDLEIN JOHN D.
申请号:
NZ62812613
公开号:
NZ628126A
申请日:
2013.02.15
申请国别(地区):
NZ
年份:
2016
代理人:
摘要:
Disclosed is a therapeutic composition, comprising a histidyl-tRNA synthetase (HRS) polypeptide of 500-506 amino acids in length that is least 90% identical to SEQ ID NO:70 (HRS(1-506)) and lacks residues 507-509 of SEQ ID NO:1, wherein the composition is: a) at least about 95% pure; b) less than about 5% aggregated; and c) has endotoxin levels of less than about 10 EU/mg of protein.