University of Cincinnati;Ventana Medical Systems, Inc.
发明人:
Mana Mirza,Elizabeth Shaughnessy,John K. Hurley,Kristie A. Vanpatten,Gary Pestano,Georg F. Weber
申请号：
US15840611
公开号：
US20180119232A1
申请日:
2017.12.13
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present disclosure provides methods and kits that can be used to determine the grade or stage of a breast or other cancer, such as a ductal carcinoma in situ (DCIS). By determining the grade, stage, or aggressiveness of a cancer, appropriate therapeutic regiments can be selected and administered to the patient with the cancer. The method includes detecting osteopontin-c (OPN-c), wherein the presence of high amounts of OPN-c in the cancer sample indicates that the subject has a more aggressive form of cancer (e.g., grade 3).
