Nancy Ann Hosken;Michael J. Lodes;Stephan R. Targan;Raodoh Mohamath
发明人:
Robert M. Hershberg,Nancy Ann Hosken,Michael J. Lodes,Raodoh Mohamath,Stephan R. Targan
申请号：
US12036588
公开号：
US09290543B2
申请日:
2008.02.25
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Compositions and methods for the therapy and diagnosis of Inflammatory Bowel Disease (IBD), including Crohn's Disease and Ulcerative Colitis, are disclosed. Illustrative compositions comprise one or more bacterial polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of IBD.
