A novel crystalline form of n-[4-[2-(2-amino-4,7-dihydro-4-oxo-3h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid and process for its preparation
CHELIUS ERIK CHRISTOPHER INNISHANNON,REUTZEL-EDENS SUSAN MARIE INDIANAPOLIS,VAN DEN BERGHE SNOREK SHARON LAFAYETTE
申请号:
HU0204232
公开号:
HU229704B1
申请日:
2001.02.12
申请国别(地区):
HU
年份:
2014
代理人:
摘要:
The invention relates to the field of pharmaceutical and organic chemistry and provides an improved process for preparing the novel heptahydrate crystalline salt of multitargeted antifolate N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]-pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid.