Gad ASHER;Benjamin LADEUIX;YEDA RESEARCH AND DEVELOPMENT CO. LTD.;Yaarit ADAMOVICH TAMAM
发明人:
Gad ASHER,Yaarit ADAMOVICH TAMAM,Benjamin LADEUIX
申请号:
IL24838516
公开号:
IL248385D0
申请日:
2016.10.18
申请国别(地区):
IL
年份:
2017
代理人:
摘要:
Disclosed herein is a system is disclosed herein for use in the treatment of a circadian rhythm disorder, such as jet lag, and an aircraft or enclosed space in an airport terminal comprising such a system. The system is configured for exposing a subject to an atmosphere having an oxygen partial pressure which differs from a prevalent oxygen partial pressure by at least 1 k Pa. Further disclosed is an agent that modulates an activity of HIF1α, for use in the treatment of a circadian rhythm disorder, and pharmaceutical compositions and kits comprising such an agent.