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חומרים בעלי מבנה אמינוגליקוזידי ושימוש בהם לטיפול במחלות גנטיות
专利权人:
Vera FIRZON;TIMOR BAASOV;Bat-Hen EYLON;VALERY BELAKHOV;Eloxx Pharmaceuticals Ltd.
发明人:
VALERY BELAKHOV,TIMOR BAASOV,Vera FIRZON,Bat-Hen EYLON
申请号:
IL27122419
公开号:
IL271224D0
申请日:
2019.12.05
申请国别(地区):
IL
年份:
2020
代理人:
摘要:
Novel aminoglycosides, represented by Formulae (e.g., a compound of Formula A, B, I, I*, III or III*, including compounds represented by Formula Ia, I**, I*a, I*b, IIIa, III**, III*a and, III*b), as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic diseases and disorders, such as diseases and disorders associated with stop codon mutations.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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