Pharmaceutical compositions and single unit dosage forms of (S)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, or a pharmaceutically acceptable stereoisomer, prodrug, salt, solvate, hydrate, or clathrate, are provided herein. Also provided are methods of treating, managing, or preventing various disorders, such as cancer, an inflammatory disease and/or an immune-related disorder.本發明提供(S)-3-(4-((4-嗎啉基甲基)芐基)氧基)-1-氧異吲哚啉-2-基)哌啶-2,6-二酮，或醫藥學上可接受之立體異構體、前藥、鹽、溶劑合物、水合物或籠形物之醫藥組合物及單次單位劑型。亦提供治療、控制或預防諸如癌症、發炎疾病及/或免疫相關病症之各種病症的方法。
