PURPOSE: An anti-allergic composition and antibacterial composition using Stichopus japonicus Orange extract is provided to suppress degranulation of mast cells and to ensure antibacterial activity. CONSTITUTION: An allergic composition contains Stichopus japonicus Orange extract as an active ingredient. The extract is prepared using water, ethanol, acetone, or mixture thereof. The composition is a pharmaceutical composition and food composition. The antibacterial composition contains Stichopus japonicus Orange extract as an active ingredient. The composition prevents Staphylococcus aureus or Staphylococcus epidermidis.본 발명은 홍해삼 추출물을 이용한 항알러지제 조성물 및 항균제 조성물을 개시한다. 홍해삼 추출물은 비만세포의 탈과립 억제 활성을 보였으며 또한 피부 상재균인 스타필로코커스 아우레우스 및 스타필로코커스 에피더미디스에 항균 활성을 보였다.