Los Angeles Biomedical Research Institute at Flarbor-UCLA Medical Center
发明人:
Nannette Y. Yount,Michael R. Yeaman
申请号：
US16612245
公开号：
US20200123209A1
申请日:
2018.05.10
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Computational systems and methods are described for identifying new type-ll bacteriocins using a systemic consensus formula and other related criteria. Newly identified type-ll bacteriocin peptides are tested experimentally and show potent microbicidal activities. Further provided are the sequences of Newly identified type-ll bacteriocin peptides, and a method of treating an infection in a patient in need thereof, comprising administering to the patient an effective amount of a peptide comprising an amino acid sequence disclosed.
