ANDREWS, DAVID MICHAEL,STOKES, ELAINE SOPHIE ELIZABETH,TURNER, ANDREW,WARING, MICHAEL JAMES,ANDREWS, David Michael,STOKES, Elaine Sophie Elizabeth,TURNER, Andrew,WARING, Michael James
申请号：
RSP20130325
公开号：
RS52881B
申请日:
2006.10.17
申请国别(地区):
RS
年份:
2014
代理人:
摘要：
The invention concerns benzamide compounds of formula (I), wherein R1 is a C-linked pyrazole ring, which is optionally substituted by one or more groups selected from C1-4alkyl, C3-4cycloalkyl, C1-4alkoxy and C3-4cycloalkoxy； or a pharmaceutically acceptable salt or pro-drug form thereof. The invention also concerns processes for the preparation of such compounds, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours or other proliferative conditions, which are sensitive to the inhibition of histone deacetylase (HDAC).Jedinjenje, naznačeno time, da je predstavljeno sa formulom (IA)gde R2, R3 i R5 su nezavisno izabrani iz vodonika ili metila； ili neka njegova farmaceutski prihvatljiva so.Prijava sadrži još 12 patentnih zahteva.
